Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB9 | P28065 | 11/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12472216 | 0.86 | PSMB9 (0.37) | PSMB9CYP2C9PSMB8MAPTCYP2C19 | |
| SCHEMBL12467641 | 0.79 | PSMB9 (0.36) | PSMB9CYP2C9PSMB8MAPTCYP2C19 | |
| SCHEMBL15849570 | 0.79 | PSMB9 (0.36) | PSMB9CYP2C9PSMB8MAPTCYP2C19 | |
| SCHEMBL12468417 | 0.79 | PSMB9 (0.36) | PSMB9CYP2C9PSMB8MAPTCYP2C19 | |
| SCHEMBL16258958 | 0.71 | OPRM1 (0.34) | PSMB9ALDH1A1PSMB8MAPT | |
| SCHEMBL12468425 | 0.71 | PSMB9 (0.34) | PSMB9PSMB8 | |
| SCHEMBL4304535 | 0.71 | PSMB9 (0.41) | PSMB9PSMB8 | |
| SCHEMBL12472519 | 0.70 | PSMB9 (0.35) | PSMB9ALDH1A1PSMB8MAPTCYP2C19 | |
| SCHEMBL12468519 | 0.69 | PSMB9 (0.34) | PSMB9PSMB8 | |
| SCHEMBL8247428 | 0.67 | PSMB9 (0.34) | PSMB9ALDH1A1PSMB8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021717-A2 | HCV PROTEASE INHIBITORS | SEQUOIA PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |