Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB9 | P28065 | 10/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.40 |
| ▸ | MME | P08473 | 8/20 | 0.38 |
| ▸ | ACE | P12821 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12472216 | 0.80 | PSMB9 (0.37) | PSMB9PSMB8 | |
| SCHEMBL16258958 | 0.77 | OPRM1 (0.34) | PSMB9PSMB8 | |
| SCHEMBL12467633 | 0.77 | PSMB9 (0.39) | PSMB9PSMB8 | |
| SCHEMBL1655875 | 0.75 | BIRC3 (0.38) | — | |
| SCHEMBL8247428 | 0.72 | PSMB9 (0.34) | PSMB9PSMB8 | |
| SCHEMBL12472519 | 0.71 | PSMB9 (0.35) | PSMB9PSMB8 | |
| SCHEMBL7953237 | 0.71 | PSMB9 (0.35) | PSMB9PSMB8 | |
| SCHEMBL21443733 | 0.70 | GHSR (0.45) | — | |
| SCHEMBL23894863 | 0.69 | PSMB9 (0.54) | PSMB9PSMB8 | |
| SCHEMBL15624107 | 0.69 | CYP2C19 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137432-A1 | A METHOD FOR PREPARING MACROCYCLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-12 | — | — | WO | disclosed |