Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 11/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932107 | 0.84 | PPIA (0.33) | PSMB9KDM4EALDH1A1GAAMAPT | |
| SCHEMBL8244703 | 0.82 | HDAC4 (0.42) | ALDH1A1HDAC4HDAC1SMN1; SMN2 | |
| SCHEMBL19869647 | 0.80 | HDAC4 (0.38) | KDM4EALDH1A1GAAMAPTHDAC4 | |
| SCHEMBL4304535 | 0.77 | PSMB9 (0.41) | PSMB9PSMB8 | |
| SCHEMBL12472216 | 0.76 | PSMB9 (0.37) | PSMB9MAPTPSMB8HDAC4HDAC1 | |
| SCHEMBL12468463 | 0.74 | PSMB9 (0.32) | OPRM1OPRD1PSMB9PSMB8HDAC4 | |
| SCHEMBL12467655 | 0.74 | PSMB9 (0.32) | OPRM1OPRD1PSMB9PSMB8HDAC4 | |
| SCHEMBL6382019 | 0.73 | F2 (0.37) | GAAHDAC4HDAC1 | |
| SCHEMBL8249384 | 0.73 | F2 (0.37) | GAAHDAC4HDAC1 | |
| SCHEMBL7919172 | 0.72 | BIRC3 (0.39) | HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089385-B1 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-2086994-B1 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2014-11-26 | — | — | EP | disclosed |