Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 20/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 18/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 18/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784825 | 0.92 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL8554552 | 0.91 | ADRA1A (0.53) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL6785313 | 0.82 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL6785334 | 0.77 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL8658997 | 0.73 | ADRA1D (0.53) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL8655005 | 0.72 | ADRA1D (0.47) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL6786714 | 0.70 | ADRA1A (0.61) | ADRA1AADRA1DADRA1B | |
| SCHEMBL6787908 | 0.69 | ADRA1A (0.57) | ADRA1AADRA1DADRA1B | |
| SCHEMBL6785271 | 0.69 | ADRA1A (0.50) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL6782168 | 0.69 | ADRA1D (0.65) | ADRA1AADRA1DADRA1BOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268369-B1 | ALPHA SUB 1 INHIBITORS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-07-31 | — | — | US | disclosed |