Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 19/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 19/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 19/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6969563 | 0.77 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL7967228 | 0.76 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL8658997 | 0.76 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL6782168 | 0.72 | ADRA1D (0.65) | ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL7953254 | 0.72 | ADRA1A (0.52) | ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL6784825 | 0.70 | ADRA1A (0.52) | ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL6782598 | 0.70 | ADRA1A (0.54) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8554552 | 0.67 | ADRA1A (0.53) | ADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL7528253 | 0.67 | ADRA1A (0.71) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7526070 | 0.67 | ADRA1A (0.61) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790826-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0790826-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |