Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147692 | 0.79 | GPR84 (0.37) | CYP3A4CYP1A2CYP2C9CYP2C19TDP1 | |
| SCHEMBL7953262 | 0.75 | AHR (0.42) | MAPK1AHRHPGDTSHRHSD17B10 | |
| SCHEMBL1004617 | 0.74 | MAPK1 (0.32) | MAPK1AHR | |
| SCHEMBL11779597 | 0.73 | AHR (0.40) | MAPK1AHRHPGDTSHRHSD17B10 | |
| SCHEMBL11219358 | 0.71 | GRIN2D (0.52) | MAPK1AHRHPGDTSHRHSD17B10 | |
| SCHEMBL9396186 | 0.71 | MAPK1 (0.38) | MAPK1AHRHPGDTSHRHSD17B10 | |
| SCHEMBL9567411 | 0.71 | HSD17B10 (0.41) | MAPK1AHRHPGDTSHRHSD17B10 | |
| SCHEMBL11314527 | 0.71 | IDO1 (0.54) | MAPK1AHRHPGDTSHRHSD17B10 | |
| SCHEMBL9567410 | 0.71 | MAPK1 (0.38) | MAPK1AHRHPGDTSHRHSD17B10 | |
| SCHEMBL130659 | 0.70 | IDO1 (0.60) | MAPK1CYP3A4IDO1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
| US-7514519-B2 | Polymer obtained by using silsesquioxane derivative | CHISSO CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7423107-B2 | Polymer obtained with silsesquioxane derivative | CHISSO PETROCHEMICAL CORPORATION (JP) | 2008-09-09 | — | — | US | disclosed |
| EP-1686133-B1 | Organosilicon compound | CHISSO CORP (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-7375170-B2 | Organosilicon compound | CHISSO CORPORATION (JP) | 2008-05-20 | — | — | US | disclosed |
| EP-1849788-A1 | Organosilicon compound | Chisso Corporation (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1849787-A1 | Organosilicon compound | Chisso Corporation (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-7235619-B2 | Silsesquioxane derivative | CHISSO CORPORATION (JP) | 2007-06-26 | — | — | US | disclosed |
| US-20060116499-A1 | Three-dimensional ladder polymer that has, as a main chain, a silsesquioxane skeleton having a structure of the cage structure of octasilsesquioxane with two broken corners reacted with unsaturated silanes, unsaturated disilanes, unsaturated polysiloxanes, or unsaturated hydrocarbons; solvent resistance | JNC CORPORATION (JP) | 2006-06-01 | — | — | US | disclosed |
| US-7053167-B2 | Silsesquioxane derivative having functional group | CHISSO CORPORATION (JP) | 2006-05-30 | — | — | US | disclosed |
| US-20060100410-A1 | Polymer obtained with silsesquioxane derivative | JNC PETROCHEMICAL CORPORATION (JP) | 2006-05-11 | — | — | US | disclosed |
| US-20060089504-A1 | Silsesquioxane derivative having functional group | ITO KENYA | 2006-04-27 | — | — | US | disclosed |
| US-20050215807-A1 | Silsesquioxane derivative | JNC CORPORATION (JP) | 2005-09-29 | — | — | US | disclosed |
| US-20040068074-A1 | Production process for silsesquioxane derivative having functional group and silsesquioxane derivative | JNC CORPORATION (JP) | 2004-04-08 | — | — | US | disclosed |
| US-20040030084-A1 | Production process for silsesquioxane derivative and silsesquioxane derivative | JNC CORPORATION (JP) | 2004-02-12 | — | — | US | disclosed |
| US-4849388-A | DIORGANOTIN BIS/2-DIKETONATE/ | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-07-18 | — | — | US | disclosed |
| US-4749766-A | Organotin curing catalyst for vulcanizable organopolysiloxanes | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-06-07 | — | — | US | disclosed |
| US-4567135-A | DIFFUSION TRANSFER, COUPLERS OF DIFFERENT REACTION SPEEDS | FUJI PHOTO FILM CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215807-A1 | Silsesquioxane derivative | STS, SFXN1, SULT1A1 | MAPK1 1845/4885AHR 3069/4885HPGD 664/4885 |
| US-20060089504-A1 | Silsesquioxane derivative having functional group | SFXN1, STS, SRM | MAPK1 3522/4885AHR 1897/4885HPGD 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.