Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048673 | 0.85 | HSP90AB1 (0.50) | HSP90AB1ALDH1A1HSD17B10ALOX15HMGCR | |
| SCHEMBL15543252 | 0.85 | ALDH1A1 (0.42) | HSP90AB1ALDH1A1HSD17B10ALOX15GAA | |
| SCHEMBL4841923 | 0.82 | HMGCR (0.58) | HSP90AB1ALDH1A1HSD17B10ALOX15HMGCR | |
| SCHEMBL23544604 | 0.82 | HPGD (0.53) | ALDH1A1HSD17B10ALOX15GAASMN1; SMN2 | |
| SCHEMBL13284210 | 0.82 | HSP90AB1 (0.52) | HSP90AB1ALDH1A1HSD17B10ALOX15HMGCR | |
| SCHEMBL11328772 | 0.81 | GAA (0.42) | ALDH1A1HSD17B10ALOX15GAASMN1; SMN2 | |
| SCHEMBL23520996 | 0.80 | ALDH1A1 (0.56) | HSP90AB1ALDH1A1HSD17B10ALOX15HMGCR | |
| SCHEMBL10518482 | 0.80 | HSP90AB1 (0.41) | HSP90AB1ALDH1A1HSD17B10GAAHMGCR | |
| SCHEMBL15543162 | 0.80 | BAZ2B (0.44) | HSP90AB1ALDH1A1HSD17B10GAAHMGCR | |
| SCHEMBL9720571 | 0.80 | HMGCR (0.56) | ALDH1A1HMGCRSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| CN-103657631-A | Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst | MITSUBISHI GAS CHEMICAL CO | 2014-03-26 | — | — | CN | disclosed |
| CN-101632925-B | Catalyst and process for producing carboxylic acid and/or carboxylic acid anhydride using the same | MITSUBISHI GAS CHEMICAL CO | 2014-02-26 | — | — | CN | disclosed |
| WO-2001096277-A1 | METHOD FOR PRODUCING 2,3,4,6-TETRAMETHYL MANDELIC ACID AND 2,3,4,6-TETRAMETHYL MANDELIC ACID ACETATE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | WO | disclosed |
| US-5103022-A | Reacting dl-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino -1-propanone with l-acetylphenylglycine to form corresponding diastereomeric salt, deposition, isolation of l-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino-1-propanone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5057535-A | Muscle relaxants | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0200942-A2 | New derivatives of an aminoketone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1986-11-12 | — | — | EP | disclosed |
| US-4182730-A | Process for the preparation of substituted dihydrocinnamaldehydes via novel β-chlorocinnamaldehydes | GIVAUDAN CORPORATION (US) | 1980-01-08 | — | — | US | disclosed |