Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284210 | 0.89 | HSP90AB1 (0.52) | HSP90AB1HMGCRCYP3A4KMT2AMEN1 | |
| SCHEMBL4841923 | 0.85 | HMGCR (0.58) | HSP90AB1HMGCRCYP3A4KMT2AMEN1 | |
| SCHEMBL7953584 | 0.85 | HSP90AB1 (0.45) | HSP90AB1HMGCRCYP3A4KMT2AMEN1 | |
| SCHEMBL11542741 | 0.83 | ALDH1A1 (0.43) | HSP90AB1CYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL5463869 | 0.82 | GSK3B (0.46) | CYP3A4KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL8688635 | 0.80 | RAB9A (0.41) | CYP3A4KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL9896417 | 0.79 | ATM (0.39) | HMGCRCYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL10101902 | 0.79 | HSP90AB1 (0.46) | HSP90AB1HMGCRCYP3A4KMT2AMEN1 | |
| SCHEMBL28654509 | 0.76 | CA12 (0.56) | CYP3A4KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL24413933 | 0.76 | PKM (0.49) | HSP90AB1HMGCRCYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641879-A | Terazololine-one compound and application thereof | 住友化学株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-107428737-A | Terazololine-one compound and application thereof | 住友化学株式会社 | 2017-12-01 | — | — | CN | disclosed |
| CN-105263921-B | Terazololine-one compound and its application | 住友化学株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-105263921-A | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL CO | 2016-01-20 | — | — | CN | disclosed |