Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 8/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953700 | 0.77 | ALDH1A1 (0.50) | PIK3CDALDH1A1HSP90AA1MAPTPKM | |
| SCHEMBL10739647 | 0.72 | PIK3CD (0.46) | PIK3CDALDH1A1PKM | |
| SCHEMBL3750871 | 0.71 | ACE (0.44) | PIK3CDACEALDH1A1PREP | |
| SCHEMBL10340335 | 0.71 | ACE (0.44) | PIK3CDACEALDH1A1PREP | |
| SCHEMBL9409947 | 0.69 | ACE (0.54) | ACEALDH1A1PREP | |
| SCHEMBL19253042 | 0.69 | ACE (0.54) | ACEALDH1A1PREP | |
| SCHEMBL1652402 | 0.69 | ACE (0.54) | ACEALDH1A1PREP | |
| SCHEMBL6482583 | 0.67 | ACE (0.57) | ACEALDH1A1PREPPOLB | |
| SCHEMBL5778845 | 0.67 | ACE (0.57) | ACEALDH1A1PREPPOLB | |
| SCHEMBL1444662 | 0.67 | ACE (0.57) | ACEALDH1A1PREPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |