Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946464 | 0.82 | FKBP1A (0.50) | ALDH1A1PIK3CDPKMGRM5TSHR | |
| SCHEMBL7953687 | 0.77 | PIK3CD (0.46) | ALDH1A1PIK3CDHSP90AA1MAPTPKM | |
| SCHEMBL22055016 | 0.77 | PIK3CD (0.51) | ALDH1A1PIK3CDHSP90AA1MAPTPKM | |
| SCHEMBL4504302 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MAPTGRM5 | |
| SCHEMBL7960313 | 0.74 | TDP1 (0.61) | ALDH1A1TDP1L3MBTL1CA2 | |
| SCHEMBL14887797 | 0.73 | ALDH1A1 (0.53) | ALDH1A1PIK3CDHSP90AA1MAPTPKM | |
| SCHEMBL7955425 | 0.73 | TDP1 (0.45) | ALDH1A1TDP1L3MBTL1GRM5CA2 | |
| SCHEMBL7592715 | 0.72 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1CA2 | |
| SCHEMBL6794087 | 0.72 | L3MBTL1 (0.64) | ALDH1A1TDP1L3MBTL1CA2SMN1; SMN2 | |
| SCHEMBL6794093 | 0.72 | L3MBTL1 (0.64) | ALDH1A1TDP1L3MBTL1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |