SCHEMBL940116

SCHEMBL940116

O=C(O)c1c(O)cccc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 4/20 0.81
SLC5A1 P13866 2/20 0.67
HIF1A Q16665 1/20 0.61
USP2 O75604 4/20 0.56
HKDC1 Q2TB90 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
TNNI3 P19429 2/20 0.56
TNNT2 P45379 2/20 0.56
TNNC1 P63316 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
GLA P06280 1/20 0.56
CYP3A4 P08684 1/20 0.56
MAPT P10636 1/20 0.56
THRB P10828 1/20 0.56
HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL940443 0.88 SLC28A3 (0.78) SLC28A3SLC5A1HIF1ATYR
SCHEMBL943236 0.85 SLC28A3 (0.74) SLC28A3SLC5A1HIF1AUSP2HKDC1
SCHEMBL940531 0.84 SLC28A3 (0.73) SLC28A3SLC5A1HIF1ATYRSLC5A2
SCHEMBL12610400 0.84 SLC28A3 (0.71) SLC28A3SLC5A1HIF1AKDM4EMEN1
SCHEMBL12610461 0.84 SLC28A3 (0.71) SLC28A3SLC5A1HIF1AKDM4EMEN1
SCHEMBL942070 0.83 SLC28A3 (0.71) SLC28A3SLC5A1HIF1AKDM4ECYP3A4
SCHEMBL23031052 0.83 SLC28A3 (0.70) SLC28A3SLC5A1HIF1AMEN1KMT2A
SCHEMBL4367622 0.83 SLC28A3 (0.70) SLC28A3SLC5A1HIF1AMEN1KMT2A
SCHEMBL940441 0.82 SLC28A3 (0.60) SLC28A3SLC5A1HIF1AKDM4EMAPT
SCHEMBL3664789 0.82 SLC28A3 (0.69) SLC28A3SLC5A1HIF1ATYRSLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1932514-B1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR EZAKI GLICO CO (JP) 2018-11-14 EP disclosed
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE EZAKI GLICO CO., LTD. (JP) 2014-01-23 US disclosed
US-20110014141-A1 TOPICAL AGENT FOR DERMATOLOGICAL USE DSM IP ASSETS B.V. (NL) 2011-01-20 US disclosed
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide EZAKI GLICO CO., LTD. (JP) 2008-11-06 US disclosed
EP-1932514-A1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR Ezaki Glico Co., Ltd. (JP) 2008-06-18 EP disclosed
EP-1859835-A2 Topical agent for dermatological use containing 4-hydroxyphenyl-alpha-D-glucopyranoside PENTAPHARM Ltd. (CH) 2007-11-28 EP disclosed
US-20030198610-A1 Topical agent for dermatological use DSM IP ASSETS B.V. (NL) 2003-10-23 US disclosed
EP-1289489-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM Ltd. (CH) 2003-03-12 EP disclosed
WO-2001091715-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM LTD. (CH) 2001-12-06 WO disclosed
EP-0649648-B1 Skin whitening agents containing glycosides SHISEIDO CO LTD (JP) 2001-09-19 EP disclosed
EP-0649648-A2 Skin whitening agents containing glycosides SHISEIDO COMPANY LIMITED (JP) 1995-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014141-A1 TOPICAL AGENT FOR DERMATOLOGICAL USE GALE, ALPP, UGGT1 SLC28A3 2245/4885SLC5A1 1371/4885HIF1A 889/4885
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE SI, CUTA, CD44 SLC28A3 1164/4885SLC5A1 723/4885HIF1A 634/4885
US-20030198610-A1 Topical agent for dermatological use GALE, UGGT1, UGDH SLC28A3 2040/4885SLC5A1 1242/4885HIF1A 1140/4885
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide CUTA, SI, CD44 SLC28A3 977/4885SLC5A1 589/4885HIF1A 658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.