SCHEMBL7953872

SCHEMBL7953872

Cc1ccc(C(=O)O)c(CCl)c1CCl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAAO P46952 1/20 0.40
CYP1A2 P05177 1/20 0.39
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NOTUM Q6P988 3/20 0.38
MCL1 Q07820 1/20 0.37
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
GABRA4 P48169 1/20 0.36
GABRE P78334 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9294588 0.86 HAAO (0.39) HAAOCYP1A2ALDH1A1KDM4EHPGD
SCHEMBL27982368 0.85 HAAO (0.38) HAAOCYP1A2ALDH1A1KDM4EHPGD
SCHEMBL5988902 0.82 ALDH1A1 (0.55) CYP1A2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL27619492 0.78 TDP1 (0.38) CYP1A2ALDH1A1KDM4EHSD17B10NOTUM
SCHEMBL28733643 0.78 GABRP (0.42) HAAOCYP1A2ALDH1A1KDM4EHPGD
SCHEMBL9164079 0.78 L3MBTL1 (0.35) CYP1A2TSHR
SCHEMBL31633434 0.78 L3MBTL1 (0.35) CYP1A2TSHR
SCHEMBL2258690 0.76 HAAO (0.40) HAAOCYP1A2ALDH1A1KDM4EHPGD
SCHEMBL28623594 0.76 GABRP (0.40) HAAOCYP1A2ALDH1A1KDM4EHPGD
SCHEMBL11140781 0.74 HAAO (0.36) HAAOCYP1A2ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001083420-A2 METHOD OF MAKING SUBSTITUTED DIHALO AROMATIC ACID CHLORIDES OCCIDENTAL CHEMICAL CORPORATION (US) 2001-11-08 WO claimed
WO-2001083420-A2 METHOD OF MAKING SUBSTITUTED DIHALO AROMATIC ACID CHLORIDES OCCIDENTAL CHEMICAL CORPORATION (US) 2001-11-08 WO disclosed