SCHEMBL7954356

SCHEMBL7954356

CCCc1n[c]cc(C)n1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
TDP2 O95551 1/20 0.30
ABL1 P00519 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
MPI P34949 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
RAB9A P51151 1/20 0.30
DUSP3 P51452 1/20 0.30
GALK1 P51570 1/20 0.30
BLM P54132 1/20 0.30
CASP9 P55211 1/20 0.30
CASP6 P55212 1/20 0.30
RIN1 Q13671 1/20 0.30
CASP8 Q14790 1/20 0.30
PDIA6 Q15084 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293452 0.77
SCHEMBL7955941 0.77
SCHEMBL7959014 0.73
SCHEMBL796567 0.71 PDE2A (0.33)
SCHEMBL13827600 0.70 HTT (0.45) KDM4ENPC1TDP2ABL1POLB
SCHEMBL17710271 0.69 RAB9A (0.40) KDM4ENPC1MAPTHTTRAB9A
SCHEMBL52748 0.67
SCHEMBL8089336 0.65 LMNA (0.38) KDM4EPOLBMAPTNPSR1
SCHEMBL1876585 0.64
SCHEMBL895443 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211190-B1 Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
US-6200997-B1 CYCLIZATION TO GIVE OXAZOLIDINEDIONES AND TRIAZOLIDINEDIONES BASF AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed
WO-1999020615-A2 PESTICIDE SUBSTITUTED PHENYL CARBAMATES, METHODS AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM, AND USE OF THE SAME BASF AKTIENGESELLSCHAFT (DE) 1999-04-29 WO disclosed
CN-1187814-A (hetero) aryloxy-, -thio-and-aminocrotonates, preparation and use thereof BASF AG (DE) 1998-07-15 CN disclosed
CN-1161687-A Phenylacetic acid alkyl esters BASF AG (DE) 1997-10-08 CN disclosed