SCHEMBL7954597

SCHEMBL7954597

CC(CCc1ccncc1)Nc1nc(Cl)nc(S(C)(=O)=O)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.34
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 3/20 0.33
CA12 O43570 2/20 0.33
CA14 Q9ULX7 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 1/20 0.33
SCN9A Q15858 1/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
KCNH2 Q12809 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
SIRT5 Q9NXA8 1/20 0.33
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7613488 0.86 ALDH1A1 (0.33) ALDH1A1CA1CA2CA9CA12
SCHEMBL7955336 0.86 GAA (0.41) ALDH1A1CA1CA2CA9CA12
SCHEMBL7954677 0.81 GAA (0.37) ALDH1A1TSHRSCN9AKCNH2TMEM97
SCHEMBL7954573 0.78 KCNH2 (0.41) ALDH1A1KCNH2TMEM97GAATDP1
SCHEMBL7959884 0.78 L3MBTL1 (0.37) ALDH1A1CYP1A2CYP2C9CYP2C19HTT
SCHEMBL7954605 0.78 GAA (0.34) ALDH1A1CA1CA2TSHRSCN9A
SCHEMBL7955256 0.78 KCNH2 (0.36) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL7956751 0.77 KCNH2 (0.38) ALDH1A1SCN9ALMNAKCNH2TMEM97
SCHEMBL7946263 0.76 KCNH2 (0.33) ALDH1A1SCN9AKCNH2TMEM97GAA
SCHEMBL7978036 0.75 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C9CYP2C19SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284710-B1 CONTROLLING WEEDS BAYER AKTIENGESELLSCHAFT (DE) 2001-09-04 US disclosed