SCHEMBL7978036

SCHEMBL7978036

CC(CCc1ccccc1)Nc1nc(Cl)nc(NS(C)(=O)=O)n1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
SCN9A Q15858 1/20 0.44
SIRT5 Q9NXA8 1/20 0.42
NR3C1 P04150 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SLC6A3 Q01959 1/20 0.39
POLB P06746 1/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
HPGD P15428 1/20 0.39
CXCR2 P25025 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7964656 0.86 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SCN9A
SCHEMBL7960038 0.78 SCN9A (0.41) ALDH1A1SCN9ASIRT5
SCHEMBL27430762 0.76 SCN9A (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19SCN9A
SCHEMBL7955336 0.73 GAA (0.41) ALDH1A1SCN9ASIRT5LMNAPOLB
SCHEMBL12462450 0.71 ALDH1A1 (0.71) ALDH1A1CYP1A2CYP2C9CYP2C19NR3C1
SCHEMBL12462411 0.71 ALDH1A1 (0.71) ALDH1A1CYP1A2CYP2C9CYP2C19NR3C1
SCHEMBL15218455 0.71 ALDH1A1 (0.71) ALDH1A1CYP1A2CYP2C9CYP2C19NR3C1
SCHEMBL7978091 0.69 SCN9A (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SCN9A
SCHEMBL5708631 0.68 KCNH3 (0.44) ALDH1A1LMNASMN1; SMN2MEN1HTT
SCHEMBL4158998 0.68 KCNH3 (0.44) ALDH1A1LMNASMN1; SMN2MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271178-B1 APPLYING TO PLANTS; CONTROLLING WEEDS BAYER AG (DE) 2001-08-07 US disclosed
EP-0932605-A1 SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINE AS HERBICIDE BAYER AG (DE) 1999-08-04 EP disclosed
WO-1998015538-A1 SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINE AS HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-04-16 WO disclosed