Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | FABP3 | P05413 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947720 | 0.87 | MAPT (0.59) | NPSR1TTRNPC1RAB9AMAPT | |
| SCHEMBL5734604 | 0.83 | NPSR1 (0.59) | NPSR1TTRNPC1RAB9AMAPT | |
| SCHEMBL7957028 | 0.83 | RAB9A (0.59) | NPSR1TTRNPC1RAB9AMAPT | |
| Irampanel SCHEMBL678128 | 0.80 | HTR7 (0.63) | NPSR1TTRNPC1RAB9AMAPT | |
| SCHEMBL5733546 | 0.79 | NPSR1 (0.52) | NPSR1TTRNPC1RAB9AMAPT | |
| Irampanel SCHEMBL6879876 | 0.79 | HTR7 (0.62) | NPSR1TTRNPC1RAB9AMAPT | |
| SCHEMBL7947863 | 0.78 | NPSR1 (0.56) | NPSR1TTRNPC1RAB9AMAPT | |
| SCHEMBL7961394 | 0.77 | NPSR1 (0.59) | NPSR1TTRNPC1RAB9AMAPT | |
| SCHEMBL5733509 | 0.77 | NPSR1 (0.50) | NPSR1TTRNPC1RAB9AMAPT | |
| SCHEMBL7957021 | 0.77 | KDM4E (0.58) | NPSR1TTRNPC1HTTGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |