Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.56 |
| ▸ | RELA | Q04206 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957028 | 0.86 | RAB9A (0.59) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| Irampanel SCHEMBL678128 | 0.83 | HTR7 (0.63) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| SCHEMBL7954795 | 0.83 | NPSR1 (0.55) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| Irampanel SCHEMBL6879876 | 0.82 | HTR7 (0.62) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| SCHEMBL7947863 | 0.81 | NPSR1 (0.56) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| SCHEMBL5733546 | 0.80 | NPSR1 (0.52) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| SCHEMBL7957021 | 0.80 | KDM4E (0.58) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| SCHEMBL7954738 | 0.80 | NPSR1 (0.57) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| SCHEMBL7947720 | 0.80 | MAPT (0.59) | NPSR1TTRSMN1; SMN2NPC1GPR55 | |
| SCHEMBL7962009 | 0.79 | KDM4E (0.60) | NPSR1TTRSMN1; SMN2NPC1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934288-B1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2006-01-04 | — | — | EP | disclosed |
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |
| EP-0934288-A1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017652-A1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-04-30 | — | — | WO | disclosed |