Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955008 | 0.95 | ALDH1A1 (0.68) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL7937849 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL17599857 | 0.93 | ALDH1A1 (0.66) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL12849347 | 0.93 | ALDH1A1 (0.66) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL8494571 | 0.92 | ALDH1A1 (0.65) | ALDH1A1CA12CA2CA9ALOX15 | |
| Hydrochloric Acid SCHEMBL11629317 | 0.92 | ALDH1A1 (0.64) | ALDH1A1CA12CA2CA9ALOX15 | |
| Hydrochloric Acid SCHEMBL5093423 | 0.92 | ALDH1A1 (0.64) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL13426054 | 0.90 | ALDH1A1 (0.62) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL1460880 | 0.89 | CYP3A4 (0.70) | ALDH1A1CA12CA2CA9ALOX15 | |
| SCHEMBL7201051 | 0.89 | ALDH1A1 (0.86) | ALDH1A1CA12CA2CA9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1550482-A | Process for manufacture of trans-(R,R)-actinol | DSM IP资产公司 | 2004-12-01 | — | — | CN | claimed |
| EP-0915076-B1 | Process for the preparation of trans-(R,R)-actinol | HOFFMANN LA ROCHE (CH) | 2002-01-16 | — | — | EP | claimed |
| US-6187961-B1 | HYDROGENATING (R)-LEVODIONE IN PRESENCE OF HYDROGEN DONAR AND A SOLVENT OR IN PRESENCE OF HYDROGEN DONOR WHICH SIMULTANEOUSLY USED AS THE SOLVENT, AND AN AMINO-AMIDE-RUTHENIUM COMPLEX | ROCHE VITAMINS INC. | 2001-02-13 | — | — | US | claimed |
| CN-1223998-A | Process for producing trans- (R, R) -actinol | HOFFMANN LA ROCHE (CH) | 1999-07-28 | — | — | CN | claimed |
| EP-0915076-A1 | Process for the preparation of trans-(R,R)-actinol | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-12 | — | — | EP | claimed |
| EP-4262819-A1 | NANOMATERIALS COMPRISING ESTER-LINKED ACETALS | Beam Therapeutics Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230331657-A1 | NANOMATERIALS COMPRISING ESTER-LINKED ACETALS | BEAM THERAPEUTICS INC. | 2023-10-19 | — | — | US | disclosed |
| CN-116887841-A | Nanomaterials comprising ester-linked acetals | 比姆医疗股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| WO-2022140252-A1 | NANOMATERIALS COMPRISING ESTER-LINKED ACETALS | BEAM THERAPEUTICS INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| CN-107428720-B | Substituted aminotriazoles as inhibitors of acid mammalian chitinase | 昂科艾伦迪治疗法股份公司 | 2020-06-30 | — | — | CN | disclosed |
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |
| EP-3233832-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS S.A. (PL) | 2017-10-25 | — | — | EP | disclosed |
| CN-1223998-A | Process for producing trans- (R, R) -actinol | HOFFMANN LA ROCHE (CH) | 1999-07-28 | — | — | CN | disclosed |
| EP-0915076-A1 | Process for the preparation of trans-(R,R)-actinol | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-12 | — | — | EP | disclosed |
| CN-1181013-A | Anti-virus triaza compounds | RES FOUNDATION OF STATE UNIV O (US) | 1998-05-06 | — | — | CN | disclosed |
| US-4315854-A | Chromium and cobalt complex amino hydroxy azomethine dyes | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| EP-0018939-A1 | 1:2 Metal complex dyestuffs of azomethines, process for their preparation and process for dyeing and printing by using these dyestuffs | CIBA-GEIGY AG (CH) | 1980-11-12 | — | — | EP | disclosed |
| US-4167632-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1979-09-11 | — | — | US | disclosed |
| US-4122265-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1978-10-24 | — | — | US | disclosed |
| US-3951965-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331657-A1 | NANOMATERIALS COMPRISING ESTER-LINKED ACETALS | LIPA, SGMS1, SGMS2 | ALDH1A1 331/4885CA12 375/4885CA2 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.