Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29209420 | 0.81 | L3MBTL1 (0.60) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL329046 | 0.81 | L3MBTL1 (0.60) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15689740 | 0.80 | LMNA (0.58) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11187257 | 0.80 | LMNA (0.58) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6269569 | 0.79 | L3MBTL1 (0.58) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15514394 | 0.78 | KMT2A (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9217848 | 0.78 | KMT2A (0.44) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL4647843 | 0.78 | L3MBTL1 (0.52) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL7956514 | 0.78 | CHRM1 (0.56) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL1578804 | 0.77 | KMT2A (0.69) | L3MBTL1TDP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |