Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279830 | 0.83 | KMT2A (0.47) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL13715537 | 0.79 | KMT2A (0.44) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL27309507 | 0.79 | KMT2A (0.44) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL2078143 | 0.79 | KMT2A (0.64) | KMT2ALMNA | |
| SCHEMBL2401919 | 0.79 | KMT2A (0.64) | KMT2ALMNA | |
| SCHEMBL7955019 | 0.78 | L3MBTL1 (0.56) | KMT2ASRCCYP2D6HDAC3HDAC4 | |
| SCHEMBL27793738 | 0.78 | L3MBTL1 (0.56) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL11187257 | 0.77 | LMNA (0.58) | KMT2ASRCCYP2D6HDAC3HDAC4 | |
| SCHEMBL15689740 | 0.77 | LMNA (0.58) | KMT2ASRCCYP2D6HDAC3HDAC4 | |
| SCHEMBL324209 | 0.76 | MMP8 (0.56) | KMT2ALMNACYP1A2SMN1; SMN2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389425-B1 | Benzotiopyranyl amines | CIBA GEIGY AG (CH) | 1995-04-26 | — | — | EP | disclosed |
| US-5071858-A | Antipsychotic benzothiopyranylamines | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0389425-A1 | Benzotiopyranyl amines | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |