Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954864 | 0.89 | CYP11B2 (0.42) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7585895 | 0.88 | KMT2A (0.56) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7960407 | 0.87 | KMT2A (0.55) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7946402 | 0.86 | KMT2A (0.43) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9065383 | 0.86 | KMT2A (0.73) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL895772 | 0.85 | MKNK1 (0.41) | KMT2AMEN1ALDH1A1MAPTCYP11B2 | |
| SCHEMBL7946379 | 0.82 | CYP11B2 (0.42) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7962101 | 0.80 | NR4A2 (0.40) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7954753 | 0.80 | NR4A2 (0.41) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7965546 | 0.79 | NR4A2 (0.40) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |