Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962938 | 0.91 | CYP11B2 (0.36) | NR4A2KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8328200 | 0.91 | CHRNB1 (0.35) | NR4A2KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL2157354 | 0.90 | MKNK1 (0.39) | NR4A2CYP11B2CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL7962101 | 0.89 | NR4A2 (0.40) | NR4A2KMT2AMEN1GABRA1GABRG2 | |
| SCHEMBL7961198 | 0.82 | MEN1 (0.34) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2157391 | 0.81 | CYP11B2 (0.40) | KMT2AMEN1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7961758 | 0.80 | FPR1 (0.35) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7955055 | 0.79 | KMT2A (0.55) | NR4A2KMT2AMEN1GABRA1GABRG2 | |
| SCHEMBL7964717 | 0.78 | ALDH1A1 (0.40) | NR4A2KMT2AMEN1GABRA1GABRG2 | |
| SCHEMBL7967732 | 0.77 | CYP11B2 (0.39) | CYP11B1CYP11B2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |