Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.41 |
| ▸ | MMP3 | P08254 | 7/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 9/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840534 | 1.00 | MMP1 (0.41) | MMP1MMP3MMP2MMP8MMP7 | |
| SCHEMBL7838011 | 0.84 | BMP1 (0.34) | MMP1MMP3MMP2BMP1 | |
| SCHEMBL7828238 | 0.82 | MMP1 (0.44) | MMP1MMP3MMP2MMP8MMP7 | |
| SCHEMBL7843485 | 0.81 | MMP1 (0.41) | MMP1MMP3MMP2MMP8MMP7 | |
| SCHEMBL7843490 | 0.81 | MMP1 (0.41) | MMP1MMP3MMP2MMP8MMP7 | |
| SCHEMBL6221572 | 0.80 | MMP1 (0.41) | MMP1MMP3MMP2MMP8MMP7 | |
| SCHEMBL6221567 | 0.80 | MMP1 (0.41) | MMP1MMP3MMP2MMP8MMP7 | |
| SCHEMBL7839515 | 0.78 | MMP1 (0.47) | MMP1MMP3MMP2MMP8MMP7 | |
| SCHEMBL7955133 | 0.71 | ADAM17 (0.55) | MMP1MMP3MMP2MMP8MMP7 | |
| SCHEMBL7955135 | 0.71 | ADAM17 (0.55) | MMP1MMP3MMP2MMP8MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281363-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; AUTOIMMUNE DISORDERS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |