Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17394562 | 0.81 | HTR2A (0.52) | HTR2ACYP3A4KDM4EGAATDP1 | |
| SCHEMBL7955089 | 0.81 | HTR2A (0.52) | HTR2ACYP3A4KDM4EGAATDP1 | |
| SCHEMBL900127 | 0.76 | HTR2A (0.52) | HTR2ACYP3A4KDM4EGAATDP1 | |
| SCHEMBL17388702 | 0.75 | TAAR1 (0.45) | HTR2ACYP3A4GAATDP1MEN1 | |
| SCHEMBL5998551 | 0.75 | APLNR (0.59) | HTR2ACYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL16033288 | 0.74 | ALDH1A1 (0.54) | CYP3A4KDM4EGAATDP1MEN1 | |
| SCHEMBL30600118 | 0.73 | TAAR1 (0.65) | HTR2ACYP3A4KDM4EGAATDP1 | |
| SCHEMBL12845585 | 0.73 | TAAR1 (0.65) | HTR2ACYP3A4KDM4EGAATDP1 | |
| SCHEMBL2095190 | 0.72 | TUBB4A (0.37) | CYP3A4GAAMEN1HTTKMT2A | |
| SCHEMBL7003956 | 0.72 | CYP3A4 (0.48) | HTR2ACYP3A4KDM4EGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |