Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 2/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239677 | 0.82 | MAPK1 (0.36) | ALDH1A1KDM4EHPGDGLACYP1A2 | |
| SCHEMBL8031085 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGLANPSR1 | |
| SCHEMBL3233849 | 0.78 | KDM4E (0.35) | ALDH1A1KDM4EHPGDGLACYP1A2 | |
| SCHEMBL3232271 | 0.77 | ATM (0.46) | ALDH1A1KDM4EHPGDNPSR1GSK3A | |
| SCHEMBL3237824 | 0.75 | ATM (0.41) | ALDH1A1KDM4EHPGDNPSR1ADORA2A | |
| SCHEMBL8041792 | 0.74 | PIK3CB (0.43) | ADORA2ADYRK1AEPHB3MAPK1PRMT5 | |
| SCHEMBL20551217 | 0.74 | KDM4E (0.47) | ALDH1A1KDM4EHPGDGLACYP1A2 | |
| SCHEMBL8049615 | 0.74 | EPHB3 (0.40) | ALDH1A1KDM4EHPGDNPSR1GSK3A | |
| SCHEMBL3235770 | 0.73 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EHPGDNPSR1ADORA2A | |
| SCHEMBL3264079 | 0.73 | ATM (0.39) | ALDH1A1KDM4EHPGDNPSR1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027114-A1 | USE OF PYRAZOLE-PYRIDINE DERIVATIVES AND ITS SALTS FOR TREATING OR REVENTIN OSTEOPOROSIS | CHOONGWAE PHARMA CORPORATION (KR) | 2010-03-11 | — | — | WO | disclosed |