Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237824 | 0.94 | ATM (0.41) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL3107285 | 0.91 | KDM4E (0.39) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL7952511 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL3235770 | 0.87 | SMN1; SMN2 (0.39) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL13099804 | 0.83 | ADORA3 (0.40) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL3264079 | 0.83 | ATM (0.39) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL3264260 | 0.82 | EPHB3 (0.41) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL8049615 | 0.82 | EPHB3 (0.40) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL3232271 | 0.82 | ATM (0.46) | ALDH1A1CASP1ATMKDM4EHPGD | |
| SCHEMBL7955207 | 0.82 | ALDH1A1 (0.37) | ALDH1A1CASP1ATMKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038385-A2 | NOVEL COMPOUNDS HAVING INDAZOLE FRAMEWORKS, METHODS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHOONGWAE PHARMA CORPORATION (KR) | 2009-03-26 | — | — | WO | disclosed |