Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959894 | 0.93 | KEAP1 (0.38) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| SCHEMBL7956674 | 0.91 | KEAP1 (0.40) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| SCHEMBL5689205 | 0.91 | KEAP1 (0.40) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| SCHEMBL7953042 | 0.89 | KEAP1 (0.39) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| SCHEMBL7765077 | 0.88 | MMP2 (0.41) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| SCHEMBL5691126 | 0.87 | KEAP1 (0.39) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| Hydrochloric Acid SCHEMBL5506705 | 0.85 | KEAP1 (0.38) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| SCHEMBL5928160 | 0.85 | KEAP1 (0.38) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| SCHEMBL8500779 | 0.83 | KEAP1 (0.39) | KEAP1NFE2L2LMNAMMP2MMP13 | |
| SCHEMBL5031172 | 0.83 | KEAP1 (0.36) | KEAP1NFE2L2LMNAMMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169085-B1 | A VIRICIDE FOR PREVENTING AND TREATING RETROVIRAL INFECTION OR THE SPREAD OF A RETROVIRUS, INHIBITING REPLICATION OF A RETROVIRUS AND TREATING AIDS | G. D. SEARLE & COMPANY | 2001-01-02 | — | — | US | disclosed |