Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746687 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPTPOLBIDO1MAPK1 | |
| SCHEMBL5182834 | 0.78 | TSHR (0.56) | ALDH1A1MAPTIDO1CYP2C19MEN1 | |
| SCHEMBL7224442 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBIDO1CYP1A2 | |
| SCHEMBL18700362 | 0.76 | TDP1 (0.43) | ALDH1A1MAPTPOLBTDP1CYP1A2 | |
| SCHEMBL8683656 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTPOLBIDO1MAPK1 | |
| SCHEMBL5657641 | 0.76 | MAPT (0.57) | ALDH1A1MAPTPOLBIDO1MAPK1 | |
| SCHEMBL8342307 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBMAPK1TDP1 | |
| SCHEMBL11904034 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTPOLBIDO1MAPK1 | |
| SCHEMBL7297643 | 0.74 | MAPT (0.58) | ALDH1A1MAPTPOLBIDO1MAPK1 | |
| SCHEMBL9570633 | 0.74 | MAPT (0.58) | ALDH1A1MAPTPOLBIDO1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265590-B1 | NEW PROTECTED AMINO ACID DERIVATIVES USEFUL FOR PEPTIDE SYNTHESIS | HYUNDAI PHARM, IND. CO., LTD. (KR) | 2001-07-24 | — | — | US | claimed |
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | claimed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | claimed |
| US-6265590-B1 | NEW PROTECTED AMINO ACID DERIVATIVES USEFUL FOR PEPTIDE SYNTHESIS | HYUNDAI PHARM, IND. CO., LTD. (KR) | 2001-07-24 | — | — | US | disclosed |
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | disclosed |