SCHEMBL7955290

SCHEMBL7955290

Fc1cccc(Cl)c1-c1c(Cl)nc2ncnn2c1SCc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 3/20 0.37
ENPP1 P22413 6/20 0.35
P2RX7 Q99572 2/20 0.34
GAA P10253 2/20 0.33
PKM P14618 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MBOAT4 Q96T53 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.32
GFER P55789 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7957151 0.86 SMN1; SMN2 (0.38) NPC1RAB9ASMN1; SMN2ALDH1A1ENPP1
SCHEMBL7958613 0.86 ALDH1A1 (0.39) ALDH1A1ENPP1GAAPKMNPSR1
SCHEMBL7956834 0.84 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1ENPP1GAANPSR1
SCHEMBL4817458 0.84 MBOAT4 (0.36) SMN1; SMN2ALDH1A1ENPP1GAAPKM
SCHEMBL7956946 0.84 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1ENPP1GAAKMT2A
SCHEMBL7955197 0.83 ALDH1A1 (0.37) ALDH1A1ENPP1GAAPKMNPSR1
SCHEMBL4818800 0.83 ALDH1A1 (0.35) ALDH1A1ENPP1GAAPKMNPSR1
SCHEMBL7957250 0.82 ATM (0.43) SMN1; SMN2ALDH1A1ENPP1GAAKMT2A
SCHEMBL7956372 0.82 LMNA (0.40) ALDH1A1ENPP1GAAKMT2APOLB
SCHEMBL7957236 0.81 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1ENPP1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277857-B1 EXCELLENT SELECTIVE FUNGICIDAL ACTIVITY AGAINST VARIOUS CROP PHYTOPATHOGENS AMERICAN CYANAMID COMPANY 2001-08-21 US claimed
US-6277857-B1 EXCELLENT SELECTIVE FUNGICIDAL ACTIVITY AGAINST VARIOUS CROP PHYTOPATHOGENS AMERICAN CYANAMID COMPANY 2001-08-21 US disclosed