Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15046983 | 0.81 | SLC6A2 (0.63) | MEN1KMT2ACYP3A4SLC6A2SLC6A4 | |
| SCHEMBL15046986 | 0.81 | SLC6A2 (0.63) | MEN1KMT2ACYP3A4SLC6A2SLC6A4 | |
| SCHEMBL12035612 | 0.78 | MEN1 (0.68) | MEN1KMT2ACYP3A4SLC6A2SLC6A4 | |
| SCHEMBL6942616 | 0.77 | SLC6A2 (0.68) | MEN1KMT2ACYP3A4SLC6A2SLC6A4 | |
| SCHEMBL813024 | 0.77 | SLC6A2 (0.68) | MEN1KMT2ACYP3A4SLC6A2SLC6A4 | |
| SCHEMBL21666077 | 0.77 | SLC6A2 (0.68) | MEN1KMT2ACYP3A4SLC6A2SLC6A4 | |
| SCHEMBL21666074 | 0.77 | SLC6A2 (0.68) | MEN1KMT2ACYP3A4SLC6A2SLC6A4 | |
| SCHEMBL8694573 | 0.77 | IGF1R (0.42) | ALOX15 | |
| SCHEMBL28398229 | 0.75 | GID4 (0.48) | SLC6A2SLC6A4SLC6A3CYP2D6ADRA1A | |
| SCHEMBL7954783 | 0.75 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021681-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-02-25 | — | — | WO | disclosed |