SCHEMBL8694573

SCHEMBL8694573

OC1CCC(c2ccccc2)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13051102 0.83 SIGMAR1 (0.48)
SCHEMBL5709410 0.83 SIGMAR1 (0.48)
SCHEMBL28040971 0.83 SIGMAR1 (0.48)
SCHEMBL13906155 0.83 SIGMAR1 (0.48)
SCHEMBL14592022 0.82 MEN1 (0.41)
SCHEMBL5206019 0.82 MEN1 (0.41)
SCHEMBL30290975 0.82 MEN1 (0.41)
SCHEMBL7955310 0.77 MEN1 (0.41) ALOX15
SCHEMBL21666077 0.77 SLC6A2 (0.68) ALOX15
SCHEMBL21666074 0.77 SLC6A2 (0.68) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773469-A Diaryl antimicrobial agents ORTHO PHARMACEUTICAL CORPORATION (US) 1998-06-30 US disclosed
WO-1997048674-A1 DIARYL ANTIMICROBIAL AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1997-12-24 WO disclosed