SCHEMBL7955337

SCHEMBL7955337

CC(C)(C)c1cc(-c2cc(C(C)(C)C)cc3ccccc23)c2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NPC1 O15118 2/20 0.42
PLA2G1B P04054 1/20 0.42
NFKB1 P19838 1/20 0.42
CASP3 P42574 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
GPR84 Q9NQS5 1/20 0.41
KIF11 P52732 2/20 0.40
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP1B1 Q16678 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7955330 0.92 ALDH1A1 (0.42) ALDH1A1L3MBTL1NPC1PLA2G1BNFKB1
SCHEMBL28777846 0.92 GPR84 (0.40) ALDH1A1L3MBTL1NPC1PLA2G1BNFKB1
SCHEMBL29750779 0.92 GPR84 (0.40) ALDH1A1L3MBTL1NPC1PLA2G1BNFKB1
SCHEMBL22747181 0.83 CYP1A2 (0.59) ALDH1A1NPC1GPR84KIF11HIF1A
SCHEMBL26579482 0.81 CYP1A2 (0.39) ALDH1A1NPC1GPR84KIF11HIF1A
SCHEMBL7950730 0.80 NR1I2 (0.45) ALDH1A1L3MBTL1NPC1PLA2G1BNFKB1
SCHEMBL26152571 0.80 GPR84 (0.39) ALDH1A1L3MBTL1NPC1PLA2G1BNFKB1
SCHEMBL23479359 0.79 CYP2A6 (0.45) ALDH1A1L3MBTL1GPR84KIF11HIF1A
SCHEMBL720292 0.79 PTPN1 (0.57) ALDH1A1GPR84HSD17B10CYP1A2MEN1
SCHEMBL295298 0.79 KIF11 (0.38) ALDH1A1L3MBTL1NPC1PLA2G1BNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265620-B1 REACTING OLEFINIC COMPOUND WITH CARBON MONOXIDE AND HYDROGEN IN PRESENCE OF CATALYST CONTAINING METAL OF GROUP 8 TO 10 AND TRIVALENT ORANIC PHOSPHORUS COMPOUND TO PRODUCE ALDEHYDE MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-24 US disclosed