Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340106 | 0.89 | TAAR1 (0.57) | TAAR1FFAR1CASP3CASP7DAO | |
| SCHEMBL22211449 | 0.83 | TAAR1 (0.59) | TAAR1FFAR1CASP3CASP7DAO | |
| SCHEMBL8498964 | 0.82 | VNN1 (0.48) | TAAR1CASP3CASP7RIPK1MAOB | |
| SCHEMBL2290 | 0.82 | ALDH1A1 (0.60) | TAAR1FFAR1CASP3CASP7DAO | |
| SCHEMBL23662782 | 0.82 | IAPP (0.53) | IAPPDAO | |
| SCHEMBL26343023 | 0.81 | FFAR1 (0.57) | TAAR1FFAR1CASP3CASP7NR3C2 | |
| SCHEMBL7080205 | 0.81 | TAAR1 (0.49) | TAAR1FFAR1NR3C2MAOBCNR1 | |
| SCHEMBL28910429 | 0.81 | IAPP (0.62) | IAPPTAAR1 | |
| SCHEMBL10694899 | 0.81 | IAPP (0.57) | IAPPTAAR1FFAR1CASP3CASP7 | |
| SCHEMBL11066194 | 0.81 | NPC1 (0.46) | TAAR1FFAR1MAOBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |