Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.48 |
| ▸ | PDE5A | O76074 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955469 | 1.00 | L3MBTL1 (0.49) | L3MBTL1PDE4BCTSLCTSSCTSK | |
| SCHEMBL7959060 | 0.90 | PDE5A (0.53) | PDE4BPDE4DPDE5A | |
| SCHEMBL7959058 | 0.90 | PDE5A (0.53) | PDE4BPDE4DPDE5A | |
| SCHEMBL4336252 | 0.89 | PDE4B (0.61) | PDE4BCTSLCTSSCTSKPDE4D | |
| SCHEMBL7957271 | 0.88 | IRAK4 (0.48) | PDE4BPDE4DIRAK4 | |
| SCHEMBL7957275 | 0.88 | IRAK4 (0.48) | PDE4BPDE4DIRAK4 | |
| SCHEMBL7956837 | 0.86 | PDE4D (0.48) | PDE4BPDE4DPDE5A | |
| SCHEMBL7956844 | 0.86 | PDE4D (0.48) | PDE4BPDE4DPDE5A | |
| SCHEMBL7956928 | 0.86 | PDE4B (0.50) | PDE4BPDE4DPDE5AIRAK4 | |
| SCHEMBL7956937 | 0.86 | PDE4B (0.50) | PDE4BPDE4DPDE5AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326379-B1 | ERECTILE DYSFUNCTION; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. | 2001-12-04 | — | — | US | disclosed |