Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956937 | 1.00 | PDE4B (0.50) | PDE4BPDE4DIRAK4PDE5A | |
| SCHEMBL7955301 | 0.92 | PDE4B (0.57) | PDE4BPDE4DPDE5A | |
| SCHEMBL7955305 | 0.92 | PDE4B (0.57) | PDE4BPDE4DPDE5A | |
| SCHEMBL7957401 | 0.87 | PDE4D (0.50) | PDE4BPDE4DPDE5A | |
| SCHEMBL7957407 | 0.87 | PDE4D (0.50) | PDE4BPDE4DPDE5A | |
| SCHEMBL7962122 | 0.86 | PDE4B (0.53) | PDE4BPDE4DPDE5A | |
| SCHEMBL7962125 | 0.86 | PDE4B (0.53) | PDE4BPDE4DPDE5A | |
| SCHEMBL7955464 | 0.86 | L3MBTL1 (0.49) | PDE4BPDE4DIRAK4PDE5A | |
| SCHEMBL7955469 | 0.86 | L3MBTL1 (0.49) | PDE4BPDE4DIRAK4PDE5A | |
| SCHEMBL7957271 | 0.85 | IRAK4 (0.48) | PDE4BPDE4DIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326379-B1 | ERECTILE DYSFUNCTION; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. | 2001-12-04 | — | — | US | disclosed |