Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957275 | 1.00 | IRAK4 (0.48) | IRAK4PDE4BPDE4DALDH1A1HTT | |
| SCHEMBL4492103 | 0.89 | PDE4B (0.59) | PDE4BPDE4D | |
| SCHEMBL7955469 | 0.88 | L3MBTL1 (0.49) | IRAK4PDE4BPDE4D | |
| SCHEMBL7955464 | 0.88 | L3MBTL1 (0.49) | IRAK4PDE4BPDE4D | |
| SCHEMBL7956937 | 0.85 | PDE4B (0.50) | IRAK4PDE4BPDE4D | |
| SCHEMBL7956928 | 0.85 | PDE4B (0.50) | IRAK4PDE4BPDE4D | |
| SCHEMBL7959058 | 0.84 | PDE5A (0.53) | PDE4BPDE4D | |
| SCHEMBL7959060 | 0.84 | PDE5A (0.53) | PDE4BPDE4D | |
| SCHEMBL4345597 | 0.83 | PDE4B (0.67) | PDE4BPDE4D | |
| SCHEMBL7955130 | 0.83 | PDE4B (0.55) | PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326379-B1 | ERECTILE DYSFUNCTION; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. | 2001-12-04 | — | — | US | disclosed |