Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612362 | 0.93 | ALDH1A1 (0.45) | POLBALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL29905681 | 0.89 | ALDH1A1 (0.50) | POLBALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL1546827 | 0.79 | POLB (0.87) | POLBALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL5280013 | 0.76 | POLB (0.93) | POLBALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL29905605 | 0.76 | POLB (0.93) | POLBALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL18657458 | 0.76 | HSD11B1 (0.50) | POLBALDH1A1TSHRL3MBTL1MAPK1 | |
| SCHEMBL25726188 | 0.75 | HSD11B1 (0.38) | ALDH1A1HPGDTSHRMAPK1LMNA | |
| SCHEMBL5524296 | 0.75 | CA2 (0.48) | ALDH1A1HPGDTSHRMAPK1HSD11B1 | |
| SCHEMBL25355555 | 0.74 | EPHX2 (0.43) | POLBALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL2422007 | 0.74 | POLB (0.61) | POLBALDH1A1HPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |