Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656284 | 0.87 | — | — | |
| SCHEMBL24984051 | 0.83 | TSHR (0.40) | ALDH1A1ADRA1ATSHRLTA4HS1PR1 | |
| SCHEMBL30280737 | 0.81 | TSHR (0.33) | ALDH1A1TSHRPOLB | |
| SCHEMBL7390435 | 0.76 | TSHR (0.35) | ALDH1A1TSHRPOLBMAPK1LMNA | |
| SCHEMBL19412271 | 0.76 | LTA4H (0.35) | ADRA1APRMT1LTA4HS1PR1S1PR3 | |
| SCHEMBL2804324 | 0.76 | PRMT1 (0.52) | ALDH1A1ADRA1ATSHRPRMT1LTA4H | |
| SCHEMBL3130249 | 0.76 | PAOX (0.52) | ALDH1A1TSHRS1PR1S1PR3S1PR5 | |
| SCHEMBL18768822 | 0.76 | TSHR (0.54) | ALDH1A1TSHREPHX2LMNAPAOX | |
| SCHEMBL31758279 | 0.76 | ADRA1A (0.42) | ALDH1A1ADRA1ATSHRPRMT1LTA4H | |
| SCHEMBL17009292 | 0.75 | PRMT1 (0.39) | ALDH1A1ADRA1ATSHRPRMT1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262084-B1 | Compounds that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION | 2001-07-17 | — | — | US | disclosed |