Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3865502 | 0.85 | MGAM (0.40) | NR1H2NR1H3KIF11TAAR1MGAM | |
| SCHEMBL486510 | 0.82 | NR1H2 (0.43) | NR1H2NR1H3MGAMMAOA | |
| SCHEMBL3919950 | 0.76 | NR1H2 (0.42) | NR1H2NR1H3MAOA | |
| SCHEMBL6003572 | 0.74 | MAOA (0.37) | KIF11TAAR1MAOA | |
| SCHEMBL10611414 | 0.72 | MAOA (0.40) | KIF11TAAR1MAOA | |
| SCHEMBL10346774 | 0.72 | CYP1A2 (0.39) | NR1H2NR1H3KIF11CYP3A4CYP2D6 | |
| SCHEMBL2012877 | 0.71 | MAPT (0.41) | NR1H2NR1H3TAAR1MGAMMAOA | |
| SCHEMBL18084487 | 0.70 | MGAM (0.44) | NR1H2NR1H3MGAM | |
| SCHEMBL9723719 | 0.70 | — | — | |
| SCHEMBL7960568 | 0.69 | NR1H2 (0.35) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10168191-A | — | — | None | — | — | JP | disclosed |
| US-6274754-B1 | HYDROSILYLATION; N,N-BIS(TRIMETHYLSILYL)ALLYLAMINE AND BIS(DIMETHYLSILYL)BENZENE IN PRESENCE OF PLATINUM CATALYST | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| JP-H10168191-A | ORIENTATING AGENT FOR LIQUID CRYSTAL | SUMITOMO BAKELITE CO LTD | 1998-06-23 | — | — | JP | disclosed |