SCHEMBL7956009

SCHEMBL7956009

COc1ccc(-c2ccc(-c3ccccc3Cc3ccc(F)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.52
LTA4H P09960 1/20 0.49
FFAR1 O14842 2/20 0.47
FFAR4 Q5NUL3 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
STAT3 P40763 1/20 0.47
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
TUBB2A Q13885 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766668 0.86 LTA4H (0.61) LTA4HFFAR1FFAR4MEN1KMT2A
SCHEMBL26949212 0.82 LTA4H (0.64) LTA4HMEN1KMT2AALDH1A1LMNA
SCHEMBL9407148 0.81 PTGDR2 (0.46) PTGDR2FFAR1FFAR4ALDH1A1
SCHEMBL9407146 0.81 DPP4 (0.48) PTGDR2FFAR1FFAR4KMT2AALDH1A1
Acetic Acid SCHEMBL10500211 0.79 FFAR1 (0.56) PTGDR2LTA4HFFAR1FFAR4MEN1
SCHEMBL22328712 0.78 HPGD (0.42) LTA4HFFAR1FFAR4MEN1KMT2A
SCHEMBL28251912 0.77 LTA4H (0.72) LTA4HMEN1KMT2AMAPTABCB1
SCHEMBL3794098 0.77 LTA4H (0.65) LTA4HMEN1KMT2AALDH1A1LMNA
SCHEMBL20819485 0.76 LTA4H (0.47) LTA4HFFAR1FFAR4MEN1KMT2A
SCHEMBL29484232 0.75 DPP4 (0.54) FFAR1FFAR4KMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232322-B1 SUCH AS (4'-BENZOFURAN-3-YL-BIPHENYL-4-YLOXY)-ACETIC ACID OR SALT AMERICAN HOME PRODUCTS CORPORATION 2001-05-15 US disclosed