SCHEMBL7956405

SCHEMBL7956405

O=C(O)c1ccc(Oc2cc3ccccc3cc2Oc2ccc(C(=O)O)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PYGM P11217 13/20 0.68
PYGL P06737 12/20 0.68
POLB P06746 2/20 0.61
ALDH1A1 P00352 2/20 0.54
KDM4E B2RXH2 2/20 0.54
HPGD P15428 1/20 0.54
HPSE Q9Y251 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969637 0.89 POLB (0.65) PYGMPYGLPOLBALDH1A1KDM4E
SCHEMBL29664286 0.89 POLB (0.65) PYGMPYGLPOLBALDH1A1KDM4E
SCHEMBL28650646 0.87 POLB (0.63) PYGMPYGLPOLBALDH1A1KDM4E
SCHEMBL28634306 0.86 POLB (0.61) PYGMPYGLPOLBALDH1A1KDM4E
SCHEMBL6891584 0.86 POLB (0.66) PYGMPYGLPOLBALDH1A1KDM4E
SCHEMBL27928487 0.85 POLB (0.64) PYGMPYGLPOLBKDM4EHPSE
SCHEMBL7257247 0.84 WDR5 (0.58) PYGMPYGLPOLBALDH1A1KDM4E
SCHEMBL7257602 0.84 POLB (0.59) PYGMPYGLPOLBALDH1A1KDM4E
SCHEMBL30287662 0.83 POLB (0.77) PYGMPYGLPOLBALDH1A1KDM4E
SCHEMBL522949 0.83 POLB (0.77) PYGMPYGLPOLBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277950-B1 FOR ADHESIVES, GAS SEPARATION MEMBRANES, COMPOSITE MATRICES, COATINGS, AND FOAMS NATIONAL SCIENCE COUNCIL (TW) 2001-08-21 US disclosed
US-6093790-A POLYIMIDE COATING MATERIAL COMPRISING MONOMERS HAVING PHENOLIC DIETHER AND TERT-BUTYL MOIETIES; THERMAL AND PHYSICAL PROPERTIES NATIONAL SCIENCE COUNCIL (TW) 2000-07-25 US disclosed
EP-0757702-B1 POLY (IMIDE-ETHERS) DU PONT (US) 1998-07-01 EP disclosed
US-5675020-A CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES THE UNIVERSITY OF LIVERPOOL (GB) 1997-10-07 US disclosed
EP-0757702-A1 POLY (IMIDE-ETHERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-12 EP disclosed
WO-1995029948-A1 POLY (IMIDE-ETHERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-11-09 WO disclosed
US-5434240-A Films. fibers, encapsulation, thermoplastics THE UNIVERSITY OF LIVERPOOL (GB) 1995-07-18 US disclosed