Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 14/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958424 | 0.86 | MAPT (0.44) | MAPTACACBPOLBL3MBTL1SCD | |
| SCHEMBL5634035 | 0.86 | MAPT (0.44) | MAPTACACBPOLBL3MBTL1SCD | |
| SCHEMBL7958334 | 0.86 | MAPT (0.44) | MAPTACACBPOLBL3MBTL1SCD | |
| SCHEMBL7961706 | 0.79 | MAPT (0.46) | MAPTPOLBSCDMAPK1 | |
| SCHEMBL7961398 | 0.79 | LIPG (0.57) | ACACBSCDLIPG | |
| SCHEMBL2814281 | 0.78 | MAPT (0.48) | MAPTPOLBL3MBTL1MAPK1 | |
| SCHEMBL17654114 | 0.76 | MAPT (0.66) | MAPTPOLBL3MBTL1SCDMAPK1 | |
| SCHEMBL17654181 | 0.75 | MAPT (0.54) | MAPTACACBPOLB | |
| SCHEMBL2811370 | 0.73 | HRH3 (0.54) | MAPTPOLBL3MBTL1MAPK1 | |
| SCHEMBL6121095 | 0.73 | MAPT (0.46) | MAPTPOLBL3MBTL1SCDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |