Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | BRD4 | O60885 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570553 | 1.00 | LMNA (0.67) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL14625066 | 0.94 | KMT2A (0.64) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL7952997 | 0.94 | KMT2A (0.64) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL11482525 | 0.94 | KMT2A (0.64) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL11546122 | 0.93 | LMNA (0.75) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL7462811 | 0.92 | LMNA (0.59) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL248401 | 0.92 | KMT2A (0.66) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL7956544 | 0.90 | KMT2A (0.72) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL1545262 | 0.90 | LMNA (0.63) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 | |
| SCHEMBL9869680 | 0.88 | LMNA (0.65) | LMNASMN1; SMN2BRD4KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |