Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810433 | 0.79 | ALDH1A1 (0.41) | TACR2TACR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7954836 | 0.76 | TACR2 (0.44) | TACR2TACR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8290886 | 0.75 | UTS2R (0.45) | TACR2TACR1CYP3A4HCRTR1HCRTR2 | |
| SCHEMBL7954472 | 0.72 | UTS2R (0.48) | TACR2TACR1CYP3A4UTS2R | |
| SCHEMBL7495039 | 0.72 | TACR2 (0.44) | TACR2TACR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7495025 | 0.72 | TACR2 (0.44) | TACR2TACR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8347627 | 0.71 | PDE4B (0.53) | TACR2TACR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7496041 | 0.71 | TACR2 (0.43) | TACR2TACR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7496029 | 0.71 | TACR2 (0.43) | TACR2TACR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27462564 | 0.70 | TACR2 (0.43) | TACR2TACR1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |