Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817605 | 0.95 | LTA4H (0.50) | LTA4HCHEK2 | |
| SCHEMBL11447699 | 0.84 | LTA4H (0.61) | LTA4H | |
| SCHEMBL11457974 | 0.84 | CHRNB4 (0.49) | LTA4HCHRNA3 | |
| SCHEMBL2482746 | 0.84 | NFE2L2 (0.58) | LTA4HCHRNA3CHEK2 | |
| SCHEMBL11455721 | 0.84 | LTA4H (0.48) | LTA4HCHRNA3 | |
| SCHEMBL11448511 | 0.84 | CHRNA3 (0.50) | LTA4HCHRNA3CHEK2 | |
| SCHEMBL11456190 | 0.84 | LTA4H (0.48) | LTA4HCHRNA3 | |
| SCHEMBL11447734 | 0.84 | LTA4H (0.67) | LTA4HCHRNA3 | |
| SCHEMBL6610063 | 0.84 | LTA4H (0.57) | LTA4H | |
| Hydrochloric Acid SCHEMBL3963860 | 0.83 | NFE2L2 (0.56) | LTA4HCHRNA3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297274-B1 | SUBSTITUTED 5-HYDROXYFURANONES | WARNER-LAMBERT COMPANY | 2001-10-02 | — | — | US | claimed |
| WO-1997037985-A1 | NONPEPTIDE ENDOTHELIN ANTAGONISTS WITH INCREASED WATER SOLUBILITY | WARNER-LAMBERT COMPANY (US) | 1997-10-16 | — | — | WO | claimed |
| US-6297274-B1 | SUBSTITUTED 5-HYDROXYFURANONES | WARNER-LAMBERT COMPANY | 2001-10-02 | — | — | US | disclosed |
| WO-1997037985-A1 | NONPEPTIDE ENDOTHELIN ANTAGONISTS WITH INCREASED WATER SOLUBILITY | WARNER-LAMBERT COMPANY (US) | 1997-10-16 | — | — | WO | disclosed |