Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958300 | 0.83 | KMT2A (0.53) | KMT2AMEN1ALDH1A1CA12CA9 | |
| SCHEMBL7956458 | 0.81 | POLB (0.51) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7958986 | 0.81 | HTR7 (0.51) | KMT2AMEN1ALDH1A1CYP2C19HTR1A | |
| SCHEMBL7956813 | 0.80 | GAA (0.50) | KMT2AMEN1CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7956239 | 0.79 | CYP19A1 (0.46) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5564069 | 0.79 | SETDB1 (0.55) | SETDB1MC4RCYP2C19HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL8336633 | 0.77 | SETDB1 (0.53) | SETDB1MC4RALDH1A1CYP2C19HTR1A | |
| SCHEMBL7947475 | 0.75 | KMT2A (0.52) | KMT2AALDH1A1HTR1ASMN1; SMN2 | |
| SCHEMBL5341195 | 0.73 | MC4R (0.51) | SETDB1MC4RKMT2AMEN1CYP2C19 | |
| SCHEMBL7958994 | 0.72 | GFER (0.50) | KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |