Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958300 | 0.89 | KMT2A (0.53) | SMN1; SMN2LMNAMEN1KMT2ARAB9A | |
| SCHEMBL7956464 | 0.87 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2LMNACYP19A1MEN1 | |
| SCHEMBL7958986 | 0.86 | HTR7 (0.51) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7956239 | 0.86 | CYP19A1 (0.46) | SMN1; SMN2LMNACYP19A1MEN1KMT2A | |
| SCHEMBL7956461 | 0.82 | ALDH1A1 (0.54) | POLBSMN1; SMN2LMNACYP19A1MEN1 | |
| SCHEMBL7956809 | 0.81 | SETDB1 (0.53) | SMN1; SMN2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL7967171 | 0.78 | KMT2A (0.54) | KMT2A | |
| SCHEMBL7947618 | 0.76 | KMT2A (0.49) | MEN1KMT2ANAMPTMAPT | |
| SCHEMBL7958994 | 0.76 | GFER (0.50) | POLBSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL7956246 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNACYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |