Pyridine

Pyridine

SCHEMBL795704

[Ag].c1ccncc1.c1ccncc1.c1ccncc1.c1ccncc1

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.90
NAPRT Q6XQN6 1/20 0.90
TDP1 Q9NUW8 1/20 0.90
NOTUM Q6P988 1/20 0.39
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CYP19A1 P11511 1/20 0.32
CYP11B2 P19099 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2A6 P11509 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL11774587 1.00
Pyridine SCHEMBL6361639 1.00
Pyridine SCHEMBL25407448 1.00 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Benzene SCHEMBL10751789 0.95 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL9037865 0.95 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2
SCHEMBL34466311 0.95 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2
SCHEMBL3052767 0.95 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL933604 0.95 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL1654468 0.95
Pyridine SCHEMBL180431 0.95 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9206122-B2 Pesticidal arylpyrrolidines BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-08 US claimed
US-20150025253-A1 PESTICIDAL ARYLPYRROLIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-22 US claimed
EP-2825532-A1 PESTICIDAL ARYLPYRROLIDINES Bayer Intellectual Property GmbH (DE) 2015-01-21 EP claimed
US-20140046069-A1 PESTICIDAL ARYLPYRROLIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-02-13 US claimed
WO-2013135724-A1 PESTICIDAL ARYLPYRROLIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-09-19 WO claimed
EP-2616437-A1 PESTICIDAL ARYLPYRROLIDINES Bayer Intellectual Property GmbH (DE) 2013-07-24 EP claimed
WO-2012035011-A1 PESTICIDAL ARYLPYRROLIDINES BAYER CROPSCIENCE AG (DE) 2012-03-22 WO claimed
US-9375000-B2 Pesticidal arylpyrrolidines BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-06-28 US disclosed
EP-2956143-A1 DIFLUPREDNATE EMULSION COMPOSITION CONTAINING ANTIMICROBIAL METAL Senju Pharmaceutical Co., Ltd. (JP) 2015-12-23 EP disclosed
US-9206122-B2 Pesticidal arylpyrrolidines BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-08 US disclosed
US-20150025253-A1 PESTICIDAL ARYLPYRROLIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-22 US disclosed
EP-2825532-A1 PESTICIDAL ARYLPYRROLIDINES Bayer Intellectual Property GmbH (DE) 2015-01-21 EP disclosed
WO-2014126267-A1 DIFLUPREDNATE EMULSION COMPOSITION CONTAINING ANTIMICROBIAL METAL SENJU PHARMACEUTICAL CO., LTD. (JP) 2014-08-21 WO disclosed
US-20140046069-A1 PESTICIDAL ARYLPYRROLIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-02-13 US disclosed
WO-2013135724-A1 PESTICIDAL ARYLPYRROLIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-09-19 WO disclosed
EP-2616437-A1 PESTICIDAL ARYLPYRROLIDINES Bayer Intellectual Property GmbH (DE) 2013-07-24 EP disclosed
WO-2012035011-A1 PESTICIDAL ARYLPYRROLIDINES BAYER CROPSCIENCE AG (DE) 2012-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140046069-A1 PESTICIDAL ARYLPYRROLIDINES DDT, ACHE, CAT TSHR 356/4885NAPRT 2752/4885TDP1 3457/4885
US-20150025253-A1 PESTICIDAL ARYLPYRROLIDINES DDT, ACHE, NPEPPS TSHR 151/4885NAPRT 2365/4885TDP1 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.