Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789145 | 0.94 | GPR119 (0.42) | GPR119CYP3A4CYP2C9SLC6A9 | |
| Iodomethane SCHEMBL795775 | 0.92 | GPR119 (0.41) | GPR119CYP3A4CYP2C9SLC6A9 | |
| SCHEMBL795479 | 0.87 | CYP3A4 (0.54) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL795480 | 0.87 | CYP3A4 (0.54) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL16011132 | 0.87 | GPR119 (0.35) | GPR119SLC6A9BTK | |
| SCHEMBL796252 | 0.85 | BTK (0.38) | GPR119CYP3A4CYP2C9SLC6A9BTK | |
| SCHEMBL2598653 | 0.85 | BTK (0.38) | GPR119CYP3A4CYP2C9SLC6A9BTK | |
| SCHEMBL15022930 | 0.85 | CYP3A4 (0.54) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL2597038 | 0.85 | CYP3A4 (0.54) | GPR119CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL797766 | 0.84 | BTK (0.37) | GPR119CYP3A4CYP2C9SLC6A9BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616074-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| US-20130184257-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2013-07-18 | — | — | US | disclosed |
| WO-2012037393-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184257-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | GPR119, GPR139, GPR180 | GPR119 1/4885CYP3A4 2241/4885CYP2C9 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.