SCHEMBL795730

SCHEMBL795730

N=C(N)c1ncncn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7978635 0.87 NQO2 (0.37)
SCHEMBL31279582 0.78 F2 (0.32)
SCHEMBL1179705 0.74
SCHEMBL28633713 0.72
Hydrochloric Acid SCHEMBL628534 0.72 P2RX7 (0.41)
SCHEMBL1462055 0.72
Iodide SCHEMBL19899750 0.70 HSP90AA1 (0.35)
Pyridine SCHEMBL8144132 0.70 NAPRT (0.41)
SCHEMBL7992613 0.70
SCHEMBL24144398 0.69 ADRA2A (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4020067-A PARASITICIDES, INSECTICIDES CIBA-GEIGY CORPORATION (US) 1977-04-26 US claimed
US-3960783-A AND FROM PHENOLS, CYANURIC ACIDS, THIOLS, OR AMINES; MOLDING, LAMINATION, ADHESIVES CIBA-GEIGY CORPORATION (US) 1976-06-01 US claimed
US-20150025057-A1 Triazine-oxadiazoles NOVARTIS AG (CH) 2015-01-22 US disclosed
US-8895733-B2 Triazine-oxadiazoles NOVARTIS AG (CH) 2014-11-25 US disclosed
US-20140051676-A1 Triazine-oxadiazoles NOVARTIS AG (CH) 2014-02-20 US disclosed
EP-2616465-A1 TRIAZINE-OXADIAZOLES Novartis AG (CH) 2013-07-24 EP disclosed
CN-103221408-A Triazine-oxadiazole compounds NOVARTIS AG 2013-07-24 CN disclosed
WO-2012035023-A1 TRIAZINE-OXADIAZOLES NOVARTIS AG (CH) 2012-03-22 WO disclosed
US-4020067-A PARASITICIDES, INSECTICIDES CIBA-GEIGY CORPORATION (US) 1977-04-26 US disclosed
US-4020067-A PARASITICIDES, INSECTICIDES CIBA-GEIGY CORPORATION (US) 1977-04-26 US disclosed
US-4020067-A PARASITICIDES, INSECTICIDES CIBA-GEIGY CORPORATION (US) 1977-04-26 US disclosed
US-3960783-A AND FROM PHENOLS, CYANURIC ACIDS, THIOLS, OR AMINES; MOLDING, LAMINATION, ADHESIVES CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed